1. Plasma analyses included Cs (Cs radioimmunoassay IBL; normal 120–250 ng/ml), adrenocorticotropic hormone (ACTH) (ACTH-II IRMA; normal (10–50 pg/ml), glucose, and electrolytes determined as follows: preoperatively (8 a.m.); 1–6 h (60-min intervals) after surgery; pre-corticotropin-releasing hormone (CRH) (Corticobiss®:2 μg/kg i.v.) administration (1st postop. day at 8 a.m. and after 30, 60, 90, and 120 min. The study was completed with plasma analyses on postoperative days 2 and 3 (8 a.m.).

Das Studienprotokoll umfaßte präoperative Ausgangswerte, die spontane Sekretion (1–6 h postop.) und die stimulierte Sekretion 30 bis 120 min nach CRH (1. postop.Tag; Corticobiss®: i.v. 2 pg/kg KG) sowie Plasmaanalysen am 2. und 3. postop.Tag (8 Uhr).